Keep up to date with the latest news and updates from MorphCryst Consulting and from the wider industry.
For a newly discovered solid chemical entity as an API, one of the characteristics to establish is the aqueous solubility. Another property which is also used to define a drug substance is the melting point. For a substance to melt, energy is required; this process is described as endothermic. This is a thermodynamic property of the solid and is termed the enthalpy.
A concern from a regulatory stance, BP and Ph. Er., with progressing a potential drug molecule sulfonate salt into clinical and drug development is the formation and presence of mutagenic alkyl sulfonate impurities produced when the salt formation or salt recrystallisation was conducted in alcohol solvents.
Use this form to contact us. We'll get back to you as soon as possible.
© 2025 Morph Cryst Consulting - Company no. 16616278
All rights reserved.